1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo-
2-(4-tert-butoxycarbonyl-2-oxo-piperazin-1-yl)acetic acid
CAS: 549506-47-0
Molecular Formula: C11H18N2O5
1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo- - Names and Identifiers
1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo- - Physico-chemical Properties
| Molecular Formula | C11H18N2O5 |
| Molar Mass | 258.27 |
| Density | 1.263 |
| Boling Point | 456.2±40.0 °C(Predicted) |
| Flash Point | 229.7°C |
| Vapor Presure | 1.37E-09mmHg at 25°C |
| pKa | 3.66±0.10(Predicted) |
| Storage Condition | Sealed in dry,2-8°C |
| Refractive Index | 1.512 |
1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo- - Risk and Safety
| HS Code | 29335990 |
1-Piperazineacetic acid, 4-[(1,1-dimethylethoxy)carbonyl]-2-oxo- - Introduction
2-(a) acetic acid is an organic compound whose chemical formula is C11H16N2O5. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: about 150-152 ℃.
-Solubility: Soluble in alcohol and ester solvents, insoluble in water.
-Stability: relatively stable to light and heat.
Use:
2-(acetic acid) is commonly used as an intermediate in drug synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.
Preparation Method:
The preparation of (2-) acetic acid can usually be completed by the following steps:
1. piperazine is reacted with chloroacetic anhydride in dichloromethane to generate piperazine 4-chloroacetate.
2. React 4-chloroacetic acid piperazine with tetra-tert-butyl carbonic anhydride (t-Boc-O2CO2t) in the presence of sodium carbonate to obtain 4-chloroacetic acid).
3. Finally, the obtained acetic acid is reacted with the alcohol solution of sodium carbonate to generate the target product 2-(quartz) acetic acid.
Safety Information:
- 2-Acetic acid is a chemical and must be stored and used properly.
-Avoid inhaling its dust. Avoid contact with skin and eyes.
-Wear appropriate personal protective equipment, such as gloves, glasses and protective face masks.
-When operating in a laboratory environment, follow safe operating procedures and provide good ventilation.
-For synthetic experiments using this compound, correct chemical synthesis procedures and safe operating procedures should be followed.
Nature:
-Appearance: White crystal or crystalline powder.
-Melting point: about 150-152 ℃.
-Solubility: Soluble in alcohol and ester solvents, insoluble in water.
-Stability: relatively stable to light and heat.
Use:
2-(acetic acid) is commonly used as an intermediate in drug synthesis. It can be used to synthesize biologically active compounds, such as drugs, pesticides, etc.
Preparation Method:
The preparation of (2-) acetic acid can usually be completed by the following steps:
1. piperazine is reacted with chloroacetic anhydride in dichloromethane to generate piperazine 4-chloroacetate.
2. React 4-chloroacetic acid piperazine with tetra-tert-butyl carbonic anhydride (t-Boc-O2CO2t) in the presence of sodium carbonate to obtain 4-chloroacetic acid).
3. Finally, the obtained acetic acid is reacted with the alcohol solution of sodium carbonate to generate the target product 2-(quartz) acetic acid.
Safety Information:
- 2-Acetic acid is a chemical and must be stored and used properly.
-Avoid inhaling its dust. Avoid contact with skin and eyes.
-Wear appropriate personal protective equipment, such as gloves, glasses and protective face masks.
-When operating in a laboratory environment, follow safe operating procedures and provide good ventilation.
-For synthetic experiments using this compound, correct chemical synthesis procedures and safe operating procedures should be followed.
Last Update：2024-04-09 21:00:56
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CAS: 549506-47-0
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CAS: 549506-47-0
Tel: 18301782025
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